{"symbol":"PCNA","synonyms":["ATLD2"],"name":"proliferating cell nuclear antigen","description":"The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5111,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5111","proteins":[{"symbol":"PCNA_HUMAN","href":"/api/1.0/protein/PCNA_HUMAN"}],"hgncRootFamilies":[]}