{"symbol":"PDE3B","synonyms":["CGIPDE1","HCGIP1"],"name":"phosphodiesterase 3B, cGMP-inhibited","description":"Enables 3\u0027,5\u0027-cyclic-AMP phosphodiesterase activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of lipid catabolic process; and regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in membrane. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":5140,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5140","proteins":[{"symbol":"PDE3B_HUMAN","href":"/api/1.0/protein/PDE3B_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphodiesterases (PDE)","href":"/api/1.0/gene_family/Phosphodiesterases+%28PDE%29"}]}