{"symbol":"PDE4D","synonyms":["PDE4DN2","ACRDYS2","STRK1","DPDE3","PDE43","HSPDE4D"],"name":"phosphodiesterase 4D, cAMP-specific","description":"This gene encodes one of four mammalian counterparts to the fruit fly \u0027dunce\u0027 gene. The encoded protein has 3\u0027,5\u0027-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":5144,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5144","proteins":[{"symbol":"PDE4D_HUMAN","href":"/api/1.0/protein/PDE4D_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphodiesterases (PDE)","href":"/api/1.0/gene_family/Phosphodiesterases+%28PDE%29"}]}