{"symbol":"PDE6G","synonyms":["PDEG","RP57"],"name":"phosphodiesterase 6G, cGMP-specific, rod, gamma","description":"This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]","ncbiEntrezGeneId":5148,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5148","proteins":[{"symbol":"CNRG_HUMAN","href":"/api/1.0/protein/CNRG_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphodiesterases (PDE)","href":"/api/1.0/gene_family/Phosphodiesterases+%28PDE%29"}]}