{"symbol":"PDE7B","synonyms":["BA472E5.1"],"name":"phosphodiesterase 7B","description":"The 3\u0027,5\u0027-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3\u0027,5\u0027-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5\u0027-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009]","ncbiEntrezGeneId":27115,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27115","proteins":[{"symbol":"PDE7B_HUMAN","href":"/api/1.0/protein/PDE7B_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphodiesterases (PDE)","href":"/api/1.0/gene_family/Phosphodiesterases+%28PDE%29"}]}