{"symbol":"PDILT","synonyms":["PDIA7"],"name":"protein disulfide isomerase-like, testis expressed","description":"This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene\u0027s expression appears to be limited to the testis. [provided by RefSeq, Dec 2016]","ncbiEntrezGeneId":204474,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/204474","proteins":[{"symbol":"PDILT_HUMAN","href":"/api/1.0/protein/PDILT_HUMAN"}],"hgncRootFamilies":[{"name":"Protein disulfide isomerases (PDI)","href":"/api/1.0/gene_family/Protein+disulfide+isomerases+%28PDI%29"}]}