{"symbol":"PDLIM2","synonyms":["MYSTIQUE"],"name":"PDZ and LIM domain 2 (mystique)","description":"This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":64236,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64236","proteins":[{"symbol":"PDLI2_HUMAN","href":"/api/1.0/protein/PDLI2_HUMAN"}],"hgncRootFamilies":[]}