{"symbol":"PDLIM3","synonyms":[],"name":"PDZ and LIM domain 3","description":"The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]","ncbiEntrezGeneId":27295,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27295","proteins":[{"symbol":"PDLI3_HUMAN","href":"/api/1.0/protein/PDLI3_HUMAN"}],"hgncRootFamilies":[]}