{"symbol":"PDPK1","synonyms":["PDPK2P","PRO0461","PDK1","PDPK2"],"name":"3-phosphoinositide dependent protein kinase 1","description":"Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":5170,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5170","proteins":[{"symbol":"PDPK1_HUMAN","href":"/api/1.0/protein/PDPK1_HUMAN"}],"hgncRootFamilies":[]}