{"symbol":"PELI3","synonyms":[],"name":"pellino E3 ubiquitin protein ligase family member 3","description":"The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]","ncbiEntrezGeneId":246330,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/246330","proteins":[{"symbol":"PELI3_HUMAN","href":"/api/1.0/protein/PELI3_HUMAN"}],"hgncRootFamilies":[{"name":"Pellino E3 ubiquitin protein ligases (PELI)","href":"/api/1.0/gene_family/Pellino+E3+ubiquitin+protein+ligases+%28PELI%29"}]}