{"symbol":"PFDN5","synonyms":["MM-1","MM1","PFD5"],"name":"prefoldin subunit 5","description":"This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":5204,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5204","proteins":[{"symbol":"PFD5_HUMAN","href":"/api/1.0/protein/PFD5_HUMAN"}],"hgncRootFamilies":[]}