{"symbol":"PFKL","synonyms":["PFK-L","PFK-B","ATP-PFK"],"name":"phosphofructokinase, liver","description":"This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]","ncbiEntrezGeneId":5211,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5211","proteins":[{"symbol":"PFKAL_HUMAN","href":"/api/1.0/protein/PFKAL_HUMAN"}],"hgncRootFamilies":[]}