{"symbol":"PGGT1B","synonyms":["BGGI","GGTI"],"name":"protein geranylgeranyltransferase type I, beta subunit","description":"Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which \u0027A\u0027 is an aliphatic amino acid and \u0027X\u0027 is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]","ncbiEntrezGeneId":5229,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5229","proteins":[{"symbol":"PGTB1_HUMAN","href":"/api/1.0/protein/PGTB1_HUMAN"}],"hgncRootFamilies":[]}