{"symbol":"PHB","synonyms":["HEL-S-54E","PHB1","HEL-215"],"name":"prohibitin","description":"This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3\u0027 UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","ncbiEntrezGeneId":5245,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5245","proteins":[{"symbol":"PHB_HUMAN","href":"/api/1.0/protein/PHB_HUMAN"}],"hgncRootFamilies":[]}