{"symbol":"PI4KA","synonyms":["PI4K-ALPHA","PMGYCHA","PI4K230","PIK4CA"],"name":"phosphatidylinositol 4-kinase, catalytic, alpha","description":"This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018]","ncbiEntrezGeneId":5297,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5297","proteins":[{"symbol":"PI4KA_HUMAN","href":"/api/1.0/protein/PI4KA_HUMAN"}],"hgncRootFamilies":[]}