{"symbol":"PIGW","synonyms":["HPMRS5","GWT1"],"name":"phosphatidylinositol glycan anchor biosynthesis, class W","description":"The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]","ncbiEntrezGeneId":284098,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/284098","proteins":[{"symbol":"PIGW_HUMAN","href":"/api/1.0/protein/PIGW_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatidylinositol glycan anchor biosynthesis (PIG)","href":"/api/1.0/gene_family/Phosphatidylinositol+glycan+anchor+biosynthesis+%28PIG%29"}]}