{"symbol":"PIGX","synonyms":["PIG-X"],"name":"phosphatidylinositol glycan anchor biosynthesis, class X","description":"This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":54965,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54965","proteins":[{"symbol":"PIGX_HUMAN","href":"/api/1.0/protein/PIGX_HUMAN"}],"hgncRootFamilies":[{"name":"Phosphatidylinositol glycan anchor biosynthesis (PIG)","href":"/api/1.0/gene_family/Phosphatidylinositol+glycan+anchor+biosynthesis+%28PIG%29"}]}