{"symbol":"PIGZ","synonyms":["PIG-Z","SMP3","GPI-MT-IV"],"name":"phosphatidylinositol glycan anchor biosynthesis, class Z","description":"The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":80235,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/80235","proteins":[{"symbol":"PIGZ_HUMAN","href":"/api/1.0/protein/PIGZ_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"},{"name":"Phosphatidylinositol glycan anchor biosynthesis (PIG)","href":"/api/1.0/gene_family/Phosphatidylinositol+glycan+anchor+biosynthesis+%28PIG%29"}]}