{"symbol":"PIK3C3","synonyms":["HVPS34","VPS34"],"name":"phosphatidylinositol 3-kinase, catalytic subunit type 3","description":"Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including early endosome to late endosome transport; macroautophagy; and phosphatidylinositol-3-phosphate biosynthetic process. Acts upstream of or within autophagy and positive regulation of protein lipidation. Located in autolysosome; late endosome; and midbody. Part of phosphatidylinositol 3-kinase complex, class III. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":5289,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5289","proteins":[{"symbol":"PK3C3_HUMAN","href":"/api/1.0/protein/PK3C3_HUMAN"}],"hgncRootFamilies":[{"name":"C2 domain containing","href":"/api/1.0/gene_family/C2+domain+containing"}]}