{"symbol":"PIK3R2","synonyms":["MPPH1","MPPH","P85B","P85-BETA"],"name":"phosphoinositide-3-kinase, regulatory subunit 2 (beta)","description":"Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Apr 2019]","ncbiEntrezGeneId":5296,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5296","proteins":[{"symbol":"P85B_HUMAN","href":"/api/1.0/protein/P85B_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}