{"symbol":"PIM3","synonyms":["PIM-3"],"name":"Pim-3 proto-oncogene, serine/threonine kinase","description":"The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. [provided by RefSeq, Jun 2012]","ncbiEntrezGeneId":415116,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/415116","proteins":[{"symbol":"PIM3_HUMAN","href":"/api/1.0/protein/PIM3_HUMAN"}],"hgncRootFamilies":[]}