{"symbol":"PIR","synonyms":[],"name":"pirin (iron-binding nuclear protein)","description":"This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8544,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8544","proteins":[{"symbol":"PIR_HUMAN","href":"/api/1.0/protein/PIR_HUMAN"}],"hgncRootFamilies":[]}