{"symbol":"PIWIL1","synonyms":["HIWI","PIWI","CT80.1","MIWI"],"name":"piwi-like RNA-mediated gene silencing 1","description":"This gene encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]","ncbiEntrezGeneId":9271,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9271","proteins":[{"symbol":"PIWL1_HUMAN","href":"/api/1.0/protein/PIWL1_HUMAN"}],"hgncRootFamilies":[{"name":"Argonaute/PIWI family (AGO, PIWIL)","href":"/api/1.0/gene_family/Argonaute%24slash%24PIWI+family+%28AGO%2C+PIWIL%29"}]}