{"symbol":"PKMYT1","synonyms":["MYT1","PPP1R126"],"name":"protein kinase, membrane associated tyrosine/threonine 1","description":"This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]","ncbiEntrezGeneId":9088,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9088","proteins":[{"symbol":"PMYT1_HUMAN","href":"/api/1.0/protein/PMYT1_HUMAN"}],"hgncRootFamilies":[{"name":"Protein phosphatase 1 regulatory subunits (PPP1R)","href":"/api/1.0/gene_family/Protein+phosphatase+1+regulatory+subunits+%28PPP1R%29"}]}