{"symbol":"PKNOX2","synonyms":["PREP2"],"name":"PBX/knotted 1 homeobox 2","description":"Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009]","ncbiEntrezGeneId":63876,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/63876","proteins":[{"symbol":"PKNX2_HUMAN","href":"/api/1.0/protein/PKNX2_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}