{"symbol":"PLA2G10","synonyms":["GXSPLA2","GXPLA2","sPLA2-X"],"name":"phospholipase A2, group X","description":"This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]","ncbiEntrezGeneId":8399,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8399","proteins":[{"symbol":"PA2GX_HUMAN","href":"/api/1.0/protein/PA2GX_HUMAN"}],"hgncRootFamilies":[{"name":"Phospholipases","href":"/api/1.0/gene_family/Phospholipases"}]}