{"symbol":"PLA2G6","synonyms":["GVI","NBIA2","NBIA2A","IPLA2","CAI-PLA2","PNPLA9","INAD1","IPLA2-VIA","PARK14","IPLA2BETA","NBIA2B"],"name":"phospholipase A2, group VI (cytosolic, calcium-independent)","description":"The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]","ncbiEntrezGeneId":8398,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8398","proteins":[{"symbol":"PLPL9_HUMAN","href":"/api/1.0/protein/PLPL9_HUMAN"}],"hgncRootFamilies":[{"name":"Ankyrin repeat domain containing (ANKRD)","href":"/api/1.0/gene_family/Ankyrin+repeat+domain+containing+%28ANKRD%29"},{"name":"Phospholipases","href":"/api/1.0/gene_family/Phospholipases"},{"name":"Parkinson disease associated genes (PARK)","href":"/api/1.0/gene_family/Parkinson+disease+associated+genes+%28PARK%29"},{"name":"Patatin-like phospholipase domain containing (PNPLA)","href":"/api/1.0/gene_family/Patatin-like+phospholipase+domain+containing+%28PNPLA%29"}]}