{"symbol":"PLCB2","synonyms":["PLC-BETA-2"],"name":"phospholipase C, beta 2","description":"The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]","ncbiEntrezGeneId":5330,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5330","proteins":[{"symbol":"PLCB2_HUMAN","href":"/api/1.0/protein/PLCB2_HUMAN"}],"hgncRootFamilies":[{"name":"Phospholipases","href":"/api/1.0/gene_family/Phospholipases"},{"name":"C2 domain containing","href":"/api/1.0/gene_family/C2+domain+containing"}]}