{"symbol":"PLD2","synonyms":["PLD1C"],"name":"phospholipase D2","description":"The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]","ncbiEntrezGeneId":5338,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5338","proteins":[{"symbol":"PLD2_HUMAN","href":"/api/1.0/protein/PLD2_HUMAN"}],"hgncRootFamilies":[{"name":"Phospholipases","href":"/api/1.0/gene_family/Phospholipases"}]}