{"symbol":"PLEK","synonyms":["P47"],"name":"pleckstrin","description":"Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of supramolecular fiber organization; and regulation of phosphate metabolic process. Located in cytoplasm and ruffle membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":5341,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5341","proteins":[{"symbol":"PLEK_HUMAN","href":"/api/1.0/protein/PLEK_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"}]}