{"symbol":"PLEKHA4","synonyms":["PEPP1"],"name":"pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4","description":"This gene encodes a pleckstrin homology (PH) domain-containing protein. The PH domain is found near the N-terminus and contains a putative phosphatidylinositol 3, 4, 5-triphosphate-binding motif (PPBM). Elevated expression of this gene has been observed in some melanomas. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017]","ncbiEntrezGeneId":57664,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57664","proteins":[{"symbol":"PKHA4_HUMAN","href":"/api/1.0/protein/PKHA4_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"}]}