{"symbol":"PLEKHF1","synonyms":["LAPF","APPD","ZFYVE15","PHAFIN1"],"name":"pleckstrin homology domain containing, family F (with FYVE domain) member 1","description":"Enables phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in endosome organization; positive regulation of autophagy; and protein localization to plasma membrane. Located in endosome and lysosome. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79156,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79156","proteins":[{"symbol":"PKHF1_HUMAN","href":"/api/1.0/protein/PKHF1_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}