{"symbol":"PLEKHG1","synonyms":["ARHGEF41"],"name":"pleckstrin homology domain containing, family G (with RhoGef domain) member 1","description":"Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":57480,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57480","proteins":[{"symbol":"PKHG1_HUMAN","href":"/api/1.0/protein/PKHG1_HUMAN"}],"hgncRootFamilies":[{"name":"Pleckstrin homology domain containing (PLEKH)","href":"/api/1.0/gene_family/Pleckstrin+homology+domain+containing+%28PLEKH%29"},{"name":"Rho guanine nucleotide exchange factors (ARHGEF)","href":"/api/1.0/gene_family/Rho+guanine+nucleotide+exchange+factors+%28ARHGEF%29"}]}