{"symbol":"PLRG1","synonyms":["CWC1","TANGO4","PRL1","PRP46","PRPF46"],"name":"pleiotropic regulator 1","description":"This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]","ncbiEntrezGeneId":5356,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5356","proteins":[{"symbol":"PLRG1_HUMAN","href":"/api/1.0/protein/PLRG1_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}