{"symbol":"PNPLA8","synonyms":["IPLA2(GAMMA)","IPLA2GAMMA","PNPLA-gamma","IPLA2G","MMLA","IPLA2-2"],"name":"patatin-like phospholipase domain containing 8","description":"This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]","ncbiEntrezGeneId":50640,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/50640","proteins":[{"symbol":"PLPL8_HUMAN","href":"/api/1.0/protein/PLPL8_HUMAN"}],"hgncRootFamilies":[{"name":"Patatin-like phospholipase domain containing (PNPLA)","href":"/api/1.0/gene_family/Patatin-like+phospholipase+domain+containing+%28PNPLA%29"}]}