{"symbol":"POFUT1","synonyms":["OFUCT1","O-FUT","O-FUCT-1","O-FUC-T","DDD2","FUT12"],"name":"protein O-fucosyltransferase 1","description":"This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":23509,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23509","proteins":[{"symbol":"OFUT1_HUMAN","href":"/api/1.0/protein/OFUT1_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}