{"symbol":"POFUT2","synonyms":["C21ORF80","FUT13"],"name":"protein O-fucosyltransferase 2","description":"Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":23275,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23275","proteins":[{"symbol":"OFUT2_HUMAN","href":"/api/1.0/protein/OFUT2_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}