{"symbol":"POLD4","synonyms":["POLDS"],"name":"polymerase (DNA-directed), delta 4, accessory subunit","description":"This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3\u0027 to 5\u0027 exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]","ncbiEntrezGeneId":57804,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57804","proteins":[{"symbol":"DPOD4_HUMAN","href":"/api/1.0/protein/DPOD4_HUMAN"}],"hgncRootFamilies":[{"name":"Polymerases, DNA-directed (POL)","href":"/api/1.0/gene_family/Polymerases%2C+DNA-directed+%28POL%29"}]}