{"symbol":"POLE2","synonyms":["DPE2"],"name":"polymerase (DNA directed), epsilon 2, accessory subunit","description":"DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency. [provided by RefSeq, Jan 2017]","ncbiEntrezGeneId":5427,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5427","proteins":[{"symbol":"DPOE2_HUMAN","href":"/api/1.0/protein/DPOE2_HUMAN"}],"hgncRootFamilies":[{"name":"Polymerases, DNA-directed (POL)","href":"/api/1.0/gene_family/Polymerases%2C+DNA-directed+%28POL%29"}]}