{"symbol":"POLQ","synonyms":["PRO0327"],"name":"polymerase (DNA directed), theta","description":"Enables several functions, including catalytic activity, acting on DNA; identical protein binding activity; and magnesium ion binding activity. Involved in DNA metabolic process; negative regulation of double-strand break repair via homologous recombination; and protein homooligomerization. Located in Golgi apparatus; cytosol; and nucleoplasm. Is active in mitochondrial nucleoid; nucleus; and site of double-strand break. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":10721,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10721","proteins":[{"symbol":"DPOLQ_HUMAN","href":"/api/1.0/protein/DPOLQ_HUMAN"}],"hgncRootFamilies":[{"name":"Polymerases, DNA-directed (POL)","href":"/api/1.0/gene_family/Polymerases%2C+DNA-directed+%28POL%29"}]}