{"symbol":"POLR1A","synonyms":["RPO1-4","RPO14","RPA194","A190","AFDCIN","RPA1"],"name":"polymerase (RNA) I polypeptide A, 194kDa","description":"The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]","ncbiEntrezGeneId":25885,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25885","proteins":[{"symbol":"RPA1_HUMAN","href":"/api/1.0/protein/RPA1_HUMAN"}],"hgncRootFamilies":[{"name":"RNA polymerase subunits (POLR)","href":"/api/1.0/gene_family/RNA+polymerase+subunits+%28POLR%29"}]}