{"symbol":"POLR1E","synonyms":["PAF53"],"name":"polymerase (RNA) I polypeptide E, 53kDa","description":"Predicted to enable DNA binding activity and RNA polymerase I general transcription initiation factor binding activity. Involved in nucleolar large rRNA transcription by RNA polymerase I and transcription initiation at RNA polymerase I promoter. Located in fibrillar center and nucleoplasm. Part of RNA polymerase I complex. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":64425,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64425","proteins":[{"symbol":"RPA49_HUMAN","href":"/api/1.0/protein/RPA49_HUMAN"}],"hgncRootFamilies":[{"name":"RNA polymerase subunits (POLR)","href":"/api/1.0/gene_family/RNA+polymerase+subunits+%28POLR%29"}]}