{"symbol":"POU3F1","synonyms":["SCIP","OCT6","OTF6"],"name":"POU class 3 homeobox 1","description":"Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of DNA-templated transcription; and positive regulation of gene expression. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":5453,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5453","proteins":[{"symbol":"PO3F1_HUMAN","href":"/api/1.0/protein/PO3F1_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}