{"symbol":"PPAT","synonyms":["ATASE","PRAT","GPAT"],"name":"phosphoribosyl pyrophosphate amidotransferase","description":"The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":5471,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5471","proteins":[{"symbol":"PUR1_HUMAN","href":"/api/1.0/protein/PUR1_HUMAN"}],"hgncRootFamilies":[]}