{"symbol":"PPIB","synonyms":["B","CYP-S1","HEL-S-39","CYPB","OI9","SCYLP"],"name":"peptidylprolyl isomerase B (cyclophilin B)","description":"The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":5479,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5479","proteins":[{"symbol":"PPIB_HUMAN","href":"/api/1.0/protein/PPIB_HUMAN"}],"hgncRootFamilies":[{"name":"Peptidylprolyl isomerases","href":"/api/1.0/gene_family/Peptidylprolyl+isomerases"}]}