{"symbol":"PPP2R2A","synonyms":["B55ALPHA","PR52A","B55A","PR55alpha","PR55A"],"name":"protein phosphatase 2, regulatory subunit B, alpha","description":"The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]","ncbiEntrezGeneId":5520,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5520","proteins":[{"symbol":"2ABA_HUMAN","href":"/api/1.0/protein/2ABA_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"},{"name":"Protein phosphatase 2 regulatory subunits (PPP2R)","href":"/api/1.0/gene_family/Protein+phosphatase+2+regulatory+subunits+%28PPP2R%29"}]}