{"symbol":"PPRC1","synonyms":["PRC"],"name":"peroxisome proliferator-activated receptor gamma, coactivator-related 1","description":"The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]","ncbiEntrezGeneId":23082,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23082","proteins":[{"symbol":"PPRC1_HUMAN","href":"/api/1.0/protein/PPRC1_HUMAN"}],"hgncRootFamilies":[{"name":"RNA binding motif containing (RBM)","href":"/api/1.0/gene_family/RNA+binding+motif+containing+%28RBM%29"}]}