{"symbol":"PRCC","synonyms":["TPRC","RCCP1"],"name":"papillary renal cell carcinoma (translocation-associated)","description":"This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]","ncbiEntrezGeneId":5546,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5546","proteins":[{"symbol":"PRCC_HUMAN","href":"/api/1.0/protein/PRCC_HUMAN"}],"hgncRootFamilies":[]}