{"symbol":"PRH2","synonyms":["DB-S","PR1/PR2","PIF-S","PRP-1/PRP-2"],"name":"proline-rich protein HaeIII subfamily 2","description":"This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. In western population this locus is commonly biallelic and encodes proline-rich protein (PRP) isoforms, PRP-1 and PRP-2. The reference genome encodes the PRP-1 allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]","ncbiEntrezGeneId":5555,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5555","proteins":[],"hgncRootFamilies":[]}