{"symbol":"PRM2","synonyms":["CT94.2"],"name":"protamine 2","description":"Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":5620,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/5620","proteins":[{"symbol":"PRM2_HUMAN","href":"/api/1.0/protein/PRM2_HUMAN"}],"hgncRootFamilies":[]}